Medications

New treatment option for nonalcoholic fatty liver disease

A team led by Michael Trauner at MedUni Vienna's Division of Gastroenterology and Hepatology demonstrated the beneficial effect of synthetically produced bile acid with the active agent nor-ursodeoxycholic acid (nor-urso) ...

Diseases, Conditions, Syndromes

CFTR inhibition: The key to treating bile acid diarrhea?

Estimates are that roughly 1 percent of people in Western countries may have bile acid diarrhea, including patients with Crohn's disease, ileal resection, diarrhea-predominant irritable bowel syndrome (IBS-D), and chronic ...

Genetics

Microbiome links diet to health

The composition of the human microbiome, a complex ecosystem of microorganisms, plays a crucial role in lifelong health. Little is known, however, about the detailed molecular mechanisms linking health status to the microbiome ...

Diseases, Conditions, Syndromes

Could the solution to osteoporosis be in the bile?

Osteoporosis is a degenerative disease where the bone density and quality are reduced. This disease is associated with substantial pain and disability leading to devastating long-term physical and psychological consequences. ...

Obstetrics & gynaecology

Stillbirth risk up with high serum bile acids in pregnancy

(HealthDay)—The risk of stillbirth is increased in women with intrahepatic cholestasis of pregnancy when serum bile acids concentrations are ≥100 µmol/L or more, according to a review published in the March 2 issue of ...

Oncology & Cancer

How do metastatic tumor cells grow in lymph nodes?

The spread of cancer to a new part of the body accounts for about 90 percent of cancer deaths. Cancer cells can spread from sites of origin to other parts of the body through blood vessels (blood-borne metastasis) or the ...

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