Genetics

Genetic and mechanistic basis for rotor syndrome uncovered

The main symptom of Rotor syndrome is jaundice caused by a buildup of a substance known as conjugated bilirubin. Bilirubin is a yellow substance generated in large quantities when the body recycles red blood cells. It is ...

Pediatrics

Severe newborn jaundice could be preventable, mouse study shows

For many newborn babies, an enzyme that breaks down the molecule bilirubin doesn't activate right away. The resulting bilirubin buildup can lead to jaundice, a typically harmless condition that causes a baby's skin to temporarily ...

Diseases, Conditions, Syndromes

Alkaline phosphatase, bilirubin predict outcomes in PBC

(HealthDay)—For patients with primary biliary cirrhosis (PBC), levels of alkaline phosphatase and bilirubin predict clinical outcome, according to a meta-analysis published in the December issue of Gastroenterology.

Diseases, Conditions, Syndromes

Serum cystatin C predicts mortality with cirrhotic ascites

(HealthDay)—Serum cystatin C level is an excellent predictor of mortality in patients with cirrhotic ascites, according to a study published online Sept. 14 in the Journal of Gastroenterology and Hepatology.

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