Alzheimer's disease & dementia

Alzheimer's protein structure offers new treatment directions

The molecular structure of a protein involved in Alzheimer's disease – and the surprising discovery that it binds cholesterol – could lead to new therapeutics for the disease, Vanderbilt University investigators ...

Medical research

Human antibodies block norovirus' point of entrance into cells

A team of scientists from Baylor College of Medicine and Vanderbilt University Medical Center have determined a mechanism by which human antibodies target and block noroviruses. Their study, which appears in the Proceedings ...

Oncology & Cancer

New strategy for safer CAR T cell therapy in lymphomas

In treating aggressive lymphomas and blood cancer (leukemia), chimeric antigen receptor T cells (CAR T cells) are increasingly being used. For this therapy, immune cells are taken from patients and programmed by means of ...

Medical research

Cholesterol sets off chaotic blood vessel growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...

HIV & AIDS

Study explores barriers to HIV vaccine response

Researchers at The Scripps Research Institute (TSRI) discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines ...

Diabetes

Polycystic ovarian syndrome ups risk of type 2 diabetes

(HealthDay) -- Middle-aged women with polycystic ovary syndrome (PCOS) are at increased risk of developing type 2 diabetes, according to a prospective long-term study published online June 14 in Diabetes.

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