Medical research

Transporter imbalance implicated in schizophrenia

Alterations in the balance of two chloride ion transporters may be responsible for cognitive deficits in schizophrenia, according to a Northwestern Medicine study published in Science Advances.

Oncology & Cancer

New computational method detects disrupted pathways in cancer

Cancer is a notoriously complex disease, in part because it may be caused by mutations among hundreds or even thousands of genes. In addition, most cancers exhibit an extraordinary amount of variation among genetic mutations, ...

Medical research

Age-resistant quiescent stem cells support muscle regeneration

Researchers from the Computational Biology group at the University of Luxembourg's Luxembourg Centre for Systems Biology (LCSB) participated in an international study focusing on adult stem cells in muscle tissue. The results ...

Genetics

The line of succession in neuron function

A specific region of messenger RNAs, the 3' untranslated region (3'UTR), plays an important role for cells to function properly. During embryonic development, 3'UTRs in hundreds of RNAs lengthen exclusively in neurons, which ...

Genetics

Biological sex affects genes for body fat, cancer, birth weight

Biological sex has a small but ubiquitous influence on gene expression in almost every type of human tissue, reports a new study from Northwestern Medicine, the University of Chicago and the Centre for Genomic Regulation ...

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