Epigenetic age, a robust marker of biological aging, has been associated with obesity, low-grade inflammation and metabolic diseases. However, few studies have examined associations between different epigenetic age measures ...
Feb 16, 2023
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A new research paper titled "Immune-mediated platelet depletion augments Alzheimer's disease neuropathological hallmarks in APP-PS1 mice" has been published in the journal Aging.
Feb 15, 2023
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Aging increases the prevalence of sarcopenia and osteoporosis which are often both components of a musculoskeletal syndrome, osteosarcopenia. Osteosarcopenia is highly associated with frailty, falls, fractures, and disability, ...
Feb 8, 2023
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A new research paper titled "Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity" has been published in Aging.
Jan 31, 2023
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Dietary restriction (DR) is a highly effective and reproducible intervention that prolongs longevity in many organisms. The molecular mechanism of action of DR is tightly connected with the immune system; however, the detailed ...
Jan 25, 2023
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Although heavy drinking in young adulthood increases the risk for alcohol use disorder (AUD), not all young heavy drinkers go on to develop AUD, globally the most common substance use disorder. Research has shown that individual ...
Jan 18, 2023
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A new research paper titled "Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization" has been published in Aging.
Jan 18, 2023
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A new research paper titled "Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV" has been published in Aging.
Jan 5, 2023
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Capturing the genetic architecture of Alzheimer's disease (AD) is challenging because of the complex interplay of genetic and non-genetic factors in its etiology. It has been suggested that AD biomarkers may improve the characterization ...
Jan 3, 2023
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DNA methylation-based (DNAm) measures of biological aging associate with increased risk of morbidity and mortality, but their links with cognitive decline are less established.
Dec 29, 2022
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