Psychology & Psychiatry

Common gene variants explain 42% of antidepressant response

Antidepressants are commonly prescribed for the treatment of depression, but many individuals do not experience symptom relief from treatment. The National Institute of Mental Health's STAR*D study, the largest and longest ...

Psychology & Psychiatry

Human emotion: We report our feelings in 3-D

Like it or not and despite the surrounding debate of its merits, 3-D is the technology du jour for movie-making in Hollywood. It now turns out that even our brains use 3 dimensions to communicate emotions.

Psychology & Psychiatry

The mysterious GRIN3A and the cause of schizophrenia

Since the 1960s, psychiatrists have been hunting for substances made by the body that might accumulate in abnormally high levels to produce the symptoms associated with schizophrenia. In particular, there was a search for ...

Neuroscience

Neuron loss in schizophrenia and depression could be prevented

Gamma-aminobutyric acid (GABA) deficits have been implicated in schizophrenia and depression. In schizophrenia, deficits have been particularly well-described for a subtype of GABA neuron, the parvalbumin fast-spiking interneurons. ...

Alzheimer's disease & dementia

Worming our way to new treatments for Alzheimer's disease

According to a 2012 World Health Organization report, over 35 million people worldwide currently have dementia, a number that is expected to double by 2030 (66 million) and triple by 2050 (115 million). Alzheimer's disease, ...

Psychology & Psychiatry

Schizophrenia: A disorder of neurodevelopment and accelerated aging?

Many lines of evidence indicate that schizophrenia is a disorder of neurodevelopment. For example, genes implicated in the heritable risk for schizophrenia are also implicated in the development of nerve cells and their connections. ...

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