Psychology & Psychiatry

How fear memories get stuck in some brains

Researchers at Linköping University, Sweden, have discovered a biological mechanism that increases the strength with which fear memories are stored in the brain. The study, carried out in rats, is published in Molecular ...

Medical research

Why immunology research needs a more human focus

Vaccinology—once a hit-and-miss matter of injecting a killed or severely weakened pathogen into a patient's arm and hoping for the best—has undergone major advances with the advent of analytical technologies that permit ...

Psychology & Psychiatry

Racial discrimination affects brain microstructure

Racial discrimination increases the risk for physical and mental illnesses, and Black women suffer from diseases at significantly higher rates than White women. How traumatic experiences such as discrimination increase vulnerability ...

Oncology & Cancer

How tumors make immune cells 'go bad'

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting. The study, published today in ...

Medical research

Protein discovery reinvigorates promising new therapeutic

Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure. However, during clinical trials, ...

Genetics

Researchers ID gene critical to human immune response

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body's white blood cells to go on ...

Medical research

Sex, gender and the mechanisms of disease

Medical research did not always include women as participants or investigate the influence of sex and gender on health. This has now changed, and research is beginning to uncover ways in which sex as a biological variable ...

Obstetrics & gynaecology

Discovering a mysterious estrogen's important role in pregnancy

When a woman becomes pregnant, her levels of estriol, one of the three common estrogens that are nearly undetectable before conception, skyrocket. However, scientists never knew what this hormone does or why levels of it ...

Medical research

It takes a heart to make a better lung

Interactions between the developing heart and lungs are essential for proper growth and maturation; however, much is still unknown about the co-development of these critical organs. To provide fresh insight, a team of collaborators ...

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