Oncology & Cancer

How tumors make immune cells 'go bad'

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting. The study, published today in ...

Medical research

Protein discovery reinvigorates promising new therapeutic

Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure. However, during clinical trials, ...

Genetics

Researchers ID gene critical to human immune response

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body's white blood cells to go on ...

Medical research

Sex, gender and the mechanisms of disease

Medical research did not always include women as participants or investigate the influence of sex and gender on health. This has now changed, and research is beginning to uncover ways in which sex as a biological variable ...

Obstetrics & gynaecology

Discovering a mysterious estrogen's important role in pregnancy

When a woman becomes pregnant, her levels of estriol, one of the three common estrogens that are nearly undetectable before conception, skyrocket. However, scientists never knew what this hormone does or why levels of it ...

Medical research

It takes a heart to make a better lung

Interactions between the developing heart and lungs are essential for proper growth and maturation; however, much is still unknown about the co-development of these critical organs. To provide fresh insight, a team of collaborators ...

Diseases, Conditions, Syndromes

Antibiotic resistance outwitted by supercomputers

Scientists may have made a giant leap in fighting the biggest threat to human health by using supercomputing to keep pace with the impressive ability of diseases to evolve.

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