Alzheimer's disease & dementia

Better hygiene in wealthy nations may increase Alzheimer's risk

New research has found a "very significant" relationship between a nation's wealth and hygiene and the Alzheimer's "burden" on its population. High-income, highly industrialised countries with large urban areas and better ...

Medical research

Knockout mouse grows larger, but weaker, muscles

Although muscle cells did not reduce in size or number in mice lacking a protective antioxidant protein, they were weaker than normal muscle cells, researchers from the Barshop Institute for Longevity and Aging Studies at ...

Medical research

Central signaling response found in mitochondrial energy diseases

Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases—a diverse set of difficult-to-treat ...

Diseases, Conditions, Syndromes

Novel drug acts in unique way to protect against kidney injury

New research reveals the mechanism by which an experimental drug can protect the kidneys from sudden damage, called acute kidney injury (AKI). The findings, which appear in an upcoming issue of the Journal of the American ...

Cardiology

Researchers identify 'master coordinator' for aortic rupture

Every year, more than 16,000 Americans die as a result of what's known as an "aortic dissection"—a catastrophic rupture of the aorta, the body's largest artery. Once thought to be a simple structural failure, aortic dissection ...

Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

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