Medical research

Knockout mouse grows larger, but weaker, muscles

Although muscle cells did not reduce in size or number in mice lacking a protective antioxidant protein, they were weaker than normal muscle cells, researchers from the Barshop Institute for Longevity and Aging Studies at ...

Medical research

Discovery reshapes understanding of embryonic development

(Medical Xpress)—When a baby is born, one of the first things a parent will do is count fingers and toes. New research conducted at UC San Francisco sheds lights on how these specialized digits are formed.

Oncology & Cancer

Novel class of drugs may help treat deadly lymphoma

A new class of drugs that inhibits a 'master switch' involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai.

Medical research

When bone-eating cells gain the upper hand

Advanced osteoporosis is often the most severe sequela, or resulting condition, of plasma cell cancer (multiple myeloma). Abnormally functioning stem cells are a key causal factor.

Genetics

New technique provides novel approach to diagnosing ciliopathies

Cilia, the cell's tails and antennas, are among the most important biological structures. They line our windpipe and sweep away all the junk we inhale; they help us see, smell and reproduce. When a mutation disrupts the function ...

Medical research

Researchers discover mutation involved in neurodegeneration

A mutation that increases the level of a special class of sphingolipids—molecules important to cell structure and signaling—can lead to neurodegeneration due to problems with neuronal membranes, reports a research team ...

Medical research

Link found between insulin sensitivity, cells' powerhouses

If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat mass, and even extend ...

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