Chronic myeloid leukemia develops when a gene mutates and causes an enzyme to become hyperactive, causing blood-forming stem cells in the bone marrow to grow rapidly into abnormal cells. The enzyme, Abl-kinase, is a member ...
Nov 17, 2014
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For patients with aggressive types of leukemia and other blood cancers, quickly identifying and starting the right treatment can make all the difference.
Nov 12, 2014
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Researchers in Spain have determined how a transcription factor known as Mirror regulates tumour-like growth in the intestines of fruit flies. The scientists believe a related system may be at work in humans during the progression ...
Oct 8, 2014
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A solitary cell containing a unique abnormality can result in certain types of blood cancers known as myeloproliferative neoplasms (MPN), according to a study published in The Journal of Experimental Medicine.
Oct 6, 2014
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In an advance against the problem of cancer metastasis, Dana-Farber Cancer Institute scientists have shown that a specially developed compound can impede multiple myeloma from spreading to the bones in mice. The findings, ...
Sep 25, 2014
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Bioluminescence, nanoparticles, gene manipulation – these sound like the ideas of a science fiction writer, but, in fact, they are components of an exciting new approach to imaging local and metastatic tumors. In preclinical ...
Sep 17, 2014
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(Medical Xpress)—A new mouse model of osteogenic sarcoma, a potentially deadly form of bone cancer, shows that high levels of Notch1, a gene that helps determine cell fate, can drive osteoblasts (cells that normally lead ...
Sep 8, 2014
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A team of scientists from the University of Colorado School of Medicine has reported the breakthrough discovery of a process to expand production of stem cells used to treat cancer patients. These findings could have implications ...
Aug 29, 2014
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(Medical Xpress)—Melbourne researchers have revealed the critical importance of highly specialised immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs. These natural killer ...
Aug 14, 2014
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A new study shows that adipose-derived human stem cells, which can become vital tissues such as bone, may be highly resistant to the common chemotherapy drug methotrexate (MTX). The preliminary finding from lab testing may ...
Jul 2, 2014
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