Genetics

Another byproduct of aging: Hypermutations in the brain

Genetic mutations in early development have been implicated in several psychiatric disorders such as autism and schizophrenia, symptoms of which typically manifest during childhood and early adulthood. However, mutations ...

HIV & AIDS

Fourth person 'cured' of HIV, but is a less risky cure in sight?

AIDS researchers announced on Wednesday that a fourth person has been "cured" of HIV, but the dangerous procedure for patients also battling cancer may be little comfort for the tens of millions living with the virus worldwide.

Medical research

Intervening to stop bone loss

Bone remodeling in the body involves a balancing act between osteoblasts, cells that build bone, and osteoclasts, cells that break it down. Diseases such as osteoporosis, arthritis, and periodontitis involve bone loss, and ...

Diseases, Conditions, Syndromes

Deconstructing the mechanics of bone marrow disease

Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body's wound healing response to various forms of damage. When accompanied ...

Genetics

Researchers find that RNA exosome is key for B cell development

New research from UT Southwestern suggests that RNA exosomes—the cellular machines that degrade old molecules of RNA—play a key role in the development of B cells, which are critical to the immune system's ability to ...

Medical research

Protein discovery reinvigorates promising new therapeutic

Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure. However, during clinical trials, ...

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