Diseases, Conditions, Syndromes

Blocking gene expression improves outcomes in blood disease in models

Scientists successfully reduced the symptoms of a blood disease called myeloproliferative neoplasm in mouse models by interrupting an important regulatory pathway, according to a Northwestern Medicine study published in the ...

Medical research

Researchers report findings on the effects of fat on stem cells

You really are what you eat—especially when it comes to fats, according to a study this week in the journal Science Advances that was co-authored by Rice University undergraduate Allison Skinkle and colleagues at the Laboratory ...

Medical research

Your bones affect your appetite—and your metabolism

Your skeleton is much more than the structure supporting your muscles and other tissues. It produces hormones, too. And Mathieu Ferron knows a lot about it. The researcher at the Montreal Clinical Research Institute (IRCM) ...

Oncology & Cancer

Blocking key pathways is a way to defeat cancer stem cells

Scientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have found that in humanized mice, a cocktail of drugs blocking certain key pathways is effective in eliminating acute ...

Genetics

A new CRISPR-engineered cancer model to test therapeutics

One major challenge in cancer research is developing robust pre-clinical models for new therapies, ones that will accurately reflect a human response to a novel compound. All too often, a potential treatment that initially ...

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