Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn's Disease and rheumatoid arthritis.
Aug 11, 2017
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Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat don't sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the ...
Aug 3, 2017
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Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. Now, researchers ...
Jul 27, 2017
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Using an array of modern biochemical and structural biology techniques, researchers from Boston University School of Medicine (BUSM) have begun to unravel the mystery of how acidity influences a small protein called serum ...
Jul 27, 2017
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Titanium dioxide, one of the most-produced nanoparticles worldwide, is being used increasingly in foodstuffs. When intestinal cells absorb titanium dioxide particles, this leads to increased inflammation and damage to the ...
Jul 19, 2017
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Existing medicines could offer a new way to treat inflammatory skin conditions, researchers at the Walter and Eliza Hall Institute and the Royal Melbourne Hospital have revealed.
Jul 17, 2017
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Today, a new drug will become available for patients with bowel cancer as part of a national clinical trial; based on a scientific discovery made only two years ago at the CRUK/MRC Oxford Institute for Radiation Oncology.
Jun 30, 2017
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In the days following abdominal surgery, patients' intestinal contents pass more slowly or not at all. New research at KU Leuven (University of Leuven), Belgium, has now shown that this phenomenon—known as post-operative ...
Jun 20, 2017
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A family of cells key to the immune system's frontline defenses has been described in greater detail than ever before. A*STAR researchers hope their analysis will help those seeking to target them to treat disease.
Jun 14, 2017
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A healthy gut requires a molecule called gp96 to train the immune system to tolerate food and normal microbes, report researchers at the Medical University of South Carolina (MUSC) in the May 19, 2017 issue of Scientific ...
Jun 13, 2017
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