Immunology

Chemotherapy-induced diarrhea traced to immune cells

Some 50 to 80 percent of cancer patients taking powerful chemotherapy drugs develop diarrhea, which can be severe and in some cases life-threatening. Their problems occur when contractions in the smooth muscle lining the ...

Oncology & Cancer

Antifungal drug eliminates sleeping bowel cancer cells in mice

An antifungal medication, commonly prescribed for toenail infections, could help eliminate dormant cells within bowel tumours, according to new research funded by Cancer Research UK and published in the Journal of Experimental ...

Immunology

Colon signaling pathway key to inflammatory bowel disease

The intestine encounters more foreign substances and potential toxins than other parts of the body, so it is not surprising that a healthy gut is maintained by the tight control of immune responses. These protect against ...

Immunology

Nervous system puts the brakes on inflammation

Cells in the nervous system can "put the brakes" on the immune response to infections in the gut and lungs to prevent excessive inflammation, according to research by Weill Cornell Medicine scientists. This insight may one ...

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