Gastroenterology

Study sheds light on how IBD can develop

Inflammatory bowel disease, or IBD, describes Crohn's disease and ulcerative colitis, two chronic diseases that cause inflammation in the intestines. IBD, which affects about 3 million adults in the United States, is an autoimmune ...

Immunology

Gut immunity more developed before birth than previously thought

Most biology textbooks explain that the fetal immune system is largely undeveloped and that it learns after being exposed to the world at birth. New research from the University of Pittsburgh School of Medicine and UPMC Children's ...

Diseases, Conditions, Syndromes

Revealed: the secret superpower that makes C. difficile so deadly

A new discovery about dangerous Clostridium difficile diarrhea has identified a new way that the bacteria – and possibly others like it – cause severe disease. "C. diff" is the most common hospital-acquired infection; ...

Inflammatory disorders

Environmental chemicals increase risk of inflammatory bowel disease

Inflammatory bowel disease (IBD), a condition characterized by chronic gastrointestinal inflammation, is becoming increasingly common in industrialized countries. While researchers have identified approximately 200 genetic ...

Gastroenterology

Optimization of human small intestinal organoids

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids—miniature versions of the small intestine. This will help them to better study the functioning of the small ...

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