Immunology

Bacteria and immune cells forge a productive partnership

To prevent infection, the intestinal wall relies on the support of its own 'home-grown' army of commensal bacteria. These gut microbiota collaborate with and are in turn regulated by their host's immune system via a variety ...

Medical research

A new strategy 'raises the volume' of gut-body communication

Throughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells and, although they comprise only a small population of the total cells, they are one of the most important moderators ...

Medical research

Innate immunity: The final touch for antimicrobial defense

If bacteria enter the body, it often takes just a few minutes for the innate immune system to recognize them as foreign and set the immune defense in motion. Receptors of the immune system that recognize bacterial cell wall ...

Immunology

Inflammatory disease trigger revealed

Institute scientists have revealed a potent inflammatory molecule released by dying cells triggers inflammation during necroptosis, a recently described form of cell death linked to inflammatory disease.

Oncology & Cancer

Blocking tumor-induced inflammation impacts cancer development

Researchers at the University of California, San Diego School of Medicine report the discovery of microbial–dependent mechanisms through which some cancers mount an inflammatory response that fuels their development and ...

Medical research

Will cell therapy become a 'third pillar' of medicine?

Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers. They outlined ...

Medical research

Immune system release valve

The molecular machines that defend our body against infection don't huff and puff, but some of them The molecular machines that defend our body against infection don't huff and puff, but some of them apparently operate on ...

Immunology

Immune cells identified as 'metabolic factories' in the gut

A research team from MedUni Vienna has now demonstrated for the first time the central role of macrophages in the renewal of intestinal cells, which sheds light on the complex interplay between immune cells and tissue regeneration. ...

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