Immunology

Study reveals details of immune defense guidance system

At the beginning of an immune response, a molecule known to mobilize immune cells into the bloodstream, where they home in on infection sites, rapidly shifts position, a new study shows. Researchers say this indirectly amplifies ...

Genetics

Genetic cause of severe liver disease discovered

Primary sclerosing cholangitis, or PSC, is a rare chronic inflammatory disease of the bile ducts. It normally debuts in young adults and two thirds of patients are men. In most cases, the patient also has an inflammatory ...

Medical research

Developmental origins of eczema and psoriasis discovered

Scientists have created a highly detailed map of skin, which reveals that cellular processes from development are re-activated in cells from patients with inflammatory skin disease. The researchers from the Wellcome Sanger ...

Diseases, Conditions, Syndromes

Cure found for rare form of inflammatory bowel disease

A rare genetic condition which causes inflammatory bowel disease can be successfully treated by bone marrow transplant, according to University of Manchester and Manchester University NHS Foundation Trust researchers.

Neuroscience

Researchers study if nerve cells evolved to talk to microbes

Various diseases of the digestive tract, for example severe intestinal inflammation in humans, are closely linked to disturbances in the natural mobility of the intestine. What role the microbiome—i.e. the natural microbial ...

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