Amyloid plaques—protein clumps that are one of the hallmarks of Alzheimer's disease—occur at roughly the same level in the brains of people with Down syndrome who have Alzheimer's as they do in people with forms of hereditary, ...
Dec 13, 2022
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After decades of failure in Alzheimer's disease research, scientists are buoyed by new findings that could mark a turning point in the field, offering hope that treatment may someday slow the grim deterioration of the brain.
Dec 5, 2022
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The formation of amyloid plaques in the brain is a hallmark of Alzheimer's disease. But drugs designed to reduce accumulations of these plaques have so far yielded, at best, mixed results in clinical trials.
Dec 1, 2022
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When the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly 20 years, it had a surprising impact on attitudes about research into the disease. A survey by University ...
Nov 30, 2022
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In a recent search for gene variants associated with Alzheimer's disease (AD), several affected families showed a mutation in an enzyme called protein kinase C-alpha (PKCα). Family members with this mutation had AD; those ...
Nov 28, 2022
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The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. ...
Nov 18, 2022
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Indiana University School of Medicine researchers are investigating how the deficiency of a gene in immune cells can shape the progression of Alzheimer's disease.
Nov 3, 2022
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Alzheimer's disease is the sixth leading cause of death in the United States, affecting more than 6 million Americans, and its incidence is expected to rise in the coming decades.
Nov 2, 2022
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Partner companies Eisai and Biogen recently announced promising clinical trial results for their new Alzheimer's drug lecanemab. Over 18 months, patients treated with lecanemab experienced slower symptom progression than ...
Oct 14, 2022
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New research from the University of Cincinnati bolsters a hypothesis that Alzheimer's disease is caused by a decline in levels of a specific protein, contrary to a prevailing theory that has been recently called into question.
Oct 4, 2022
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