Alzheimer's disease & dementia

Brain tissue inflammation is key to Alzheimer's disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School ...

Alzheimer's disease & dementia

Amyloid deposits in eyes provide a peek at Alzheimer's disease risk

Amyloid plaques are protein deposits that collect between brain cells, hindering function and eventually leading to neuronal death. They are considered a hallmark of Alzheimer's disease (AD), and the focus of multiple investigations ...

Alzheimer's disease & dementia

A potential new treatment target for Alzheimer's disease

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

Alzheimer's disease & dementia

What happens in brain cells affected by Alzheimer's disease?

Affecting over 50 million people, Alzheimer's disease is the most common form of dementia and primarily occurs in people over the age of 65. The pathology of the disease in the brain is mainly characterized by two factors: ...

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