Oncology & Cancer

Cancer-fighting combination targets glioblastoma

Researchers have paired a specialized diet and a tumor-fighting drug and found the non-toxic combination helps to destroy the two major cells found in an aggressive form of brain cancer, the team reports in the online edition ...

Medical research

Targeting key gene could help lead to Down syndrome treatment

Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.

Neuroscience

Brain changes in autism traced to specific cell types

Changes in gene activity in specific brain cells are associated with the severity of autism in children and young adults with the disorder, according to a UC San Francisco study of postmortem brain tissue. The study's new ...

Genetics

Awakening stem cells to unlock the brain's regenerative potential

The human body has powerful healing abilities. But treating brain disorders is no easy task, as brain cells—neurons—have limited ability to regenerate. Nonetheless, stem cells are a form of natural backup, a vestige of ...

Neuroscience

Stem cells provide information about neuron resilience in ALS

Researchers at Karolinska Institutet in Sweden have developed a stem cell-based model to study the resilience and vulnerability of neurons in the neurodegenerative disease ALS. The results are published in the journal Stem ...

Oncology & Cancer

The unanticipated early origins of childhood brain cancer

Brain tumours are the leading cause of non-accidental death in children in Canada, but little is known about when these tumours form or how they develop. Researchers have recently identified the cells that are thought to ...

Neuroscience

Proteins stand up to nerve cell regression

A study by Duke-NUS Medical School has found that members of the multiprotein 'Integrator complex', known for its role in gene regulation, are crucial for healthy brain development in fruit flies. The findings have implications ...

Neuroscience

Growing a cerebral tract in a microscale brain model

An international research team led by The University of Tokyo modeled the growth of cerebral tracts. Using neurons derived from stem cells, they grew cortical-like spheroids. In a microdevice, the spheroids extended bundles ...

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