Medical research

Changes detected in BRCA1 breast cells before they turn cancerous

A new study funded by Cancer Research UK has mapped out some of the earliest changes that occur in seemingly healthy breast tissue long before any tumors appear, which could have significant implications for the early detection ...

Medical research

NICE approves new maintenance treatment for ovarian cancer

A new targeted treatment has been recommended by the National Institute of Health and Care Excellence (NICE) for some adults with advanced high-grade epithelial ovarian, fallopian tube or primary peritoneal cancer

Oncology & Cancer

Q&A: Genetic abnormalities and cancer risk

My mom was diagnosed with breast cancer. During her care, she was found to have a BRCA2 mutation. Her doctor suggested that my brothers and I get tested for this mutation, too. I am a 26-year-old woman, and I am not sure ...

Oncology & Cancer

Halting cancer by halting DNA repair

PARP inhibitors are rapidly transforming the treatment of ovarian, breast, prostate and other types of cancer. To develop these drugs, researchers supported by Cancer Research UK had to decipher how blocking DNA repair could ...

Oncology & Cancer

Guidance issued for genetic testing in prostate cancer

(HealthDay)—As a result of the Philadelphia Prostate Cancer Consensus Conference, hosted by Sidney Kimmel Cancer Center-Jefferson Health and the Department of Urology at Jefferson, recommendations have been developed for ...

Oncology & Cancer

A new way to target cancers using 'synthetic lethality'

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the ...

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