Researchers have identified a metabolic enzyme and pathway in some triple-negative breast cancer (TNBC) patients, which they hope could serve as a biomarker to select patients to receive targeted therapy.
Nov 16, 2021
0
55
Breast cancers that have an overactive PI3K enzyme, involved in cell growth and division, tend to be more aggressive and to spread and divide more like stem cells. But a new study by Ralitsa Madsen of University College London ...
Nov 11, 2021
0
19
Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from ...
Nov 9, 2021
0
57
Cancer onset prevention is considered to be the most important and cost-effective long-term measure for cancer prevention. However, since the molecular mechanisms by which premalignant lesions and very early cancers begin ...
Nov 8, 2021
0
35
George Washington University researchers have identified a key molecule in certain kinds of breast cancers that prevent immune cells from entering tumors and killing the cancer cells inside. The paper and its findings, published ...
Nov 3, 2021
0
191
A new study adds to the evidence that chemotherapy enhances cancer's spread beyond the primary tumor, showing how one chemo drug allows breast cancer cells to squeeze through and attach to blood vessel linings in the lungs.
Nov 2, 2021
0
1334
Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy. Researchers at the University of Alabama at Birmingham have now shown—in preclinical experiments—how ...
Oct 28, 2021
0
31
A multi-institution team of researchers led by scientists at Baylor College of Medicine has discovered a genetic signature that can identify drivers of poor outcomes in advanced estrogen-receptor positive (ER+) breast cancer, ...
Oct 28, 2021
0
55
Molecular targets for therapies that could prevent breast cancer recurrence have been identified by a group of German, Norwegian and British scientists who analyzed tumor cells that proved resistant to the original treatment. ...
Oct 25, 2021
0
8
A non-toxic, bacteria-based system developed at the University of Massachusetts Amherst can detect when it is inside a cancer cell and then release its payload of therapeutic drugs directly into the cell. The work, published ...
Oct 21, 2021
0
102
