Oxygen deprivation, or hypoxia, has been identified by A*STAR researchers as a key factor in switching the function of major cancer genes from tumor-promoting to tumor-suppressing in a breast cancer subtype, suggesting the ...
Jan 4, 2017
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As cancerous tumors fester in the body, they need an ever-increasing blood supply to deliver the oxygen and nutrients that fuel their growth. Now, a team led by University of Florida Health researchers has established how ...
Dec 21, 2016
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Even before tumors develop, breast cancer cells with a few defined molecular alterations can spread to organs, remain quiet for long periods of time, and then awaken to form aggressive, deadly breast cancer metastasis, says ...
Dec 14, 2016
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366
A biologist at The University of Texas at Dallas and his colleagues have discovered that two enzymes previously linked independently with keeping cancer cells alive actually work in tandem to spur tumor growth.
Dec 14, 2016
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211
How does a cancer cell burn calories? New research from Thomas Jefferson University shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells. The results were recently published ...
Nov 28, 2016
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176
Cancer rewires the metabolism of tumor cells, converting them into lean, mean, replicating machines. But like Olympic athletes who rely on special diets to perform, tumor cells' amped-up metabolism can also make them dependent ...
Nov 21, 2016
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Silencing SIRT2, a member of the sirtuin family of enzymes, reduces the invasiveness of basal-like breast cancer cells in culture and inhibits tumor growth in mice, according to new research led by scientists from Tufts University ...
Oct 31, 2016
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A new study has identified a mechanism used by tumors to recruit stem cells from bone and convert them into cancer-associated fibroblasts (CAFs) that facilitate tumor progression. This work, which pinpoints the specific biochemical ...
Oct 20, 2016
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A new clinical trial for women with clinically aggressive triple-negative breast cancer (TNBC) will test a novel theory: Will a diet low in an essential nutrient make TNBC cells more vulnerable to cell killing by a new cancer ...
Oct 19, 2016
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In a research study published in the journal Oncogene, scientists from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine showed that by therapeutically targeting the receptor for advanced ...
Oct 3, 2016
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