Medical research

Sensing self and non-self: New research into immune tolerance

At the most basic level, the immune system must distinguish self from non-self, that is, it must discriminate between the molecular signatures of invading pathogens (non-self antigens) and cellular constituents that usually ...

Oncology & Cancer

A leap forward in research on CAR T cell therapy

In cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of the most significant recent advances in immunotherapies targeted at cancer.

Oncology & Cancer

A T-cell power-up for tumor treatments

Cancer is the second leading cause of death in the United States. But in recent years, a revolutionary therapy has brought new hope in the fight against the disease that takes the lives of nearly 600,000 Americans each year. ...

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