The cells of most patients' cancers are resistant to a class of drugs, called proteasome inhibitors, that should kill them. When studied in the lab, these drugs are highly effective, yet hundreds of clinical trials testing ...
May 28, 2019
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Scientists are using a lot of genomic data to identify medical issues sooner in patients, but they're also using it to assist their scientific counterparts in researching diseases better.
May 15, 2019
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Large libraries of cancer cell lines—collections of cells that represent tumor types seen in cancer patients—can yield profound insights into tumors' unique genetic features and their sensitivities to current and potential ...
May 13, 2019
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31
Three years after the Zika virus swept through tropical and subtropical South America, the Caribbean, Florida, and Texas, much remains unknown about what the virus needs to infect and damage its host cells in the brain. Now ...
Apr 23, 2019
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Some 15 to 20 percent of all breast cancers are triple-negative, meaning they lack receptors for estrogen, progesterone and human epidermal growth factor type 2. They have the worst prognosis of all breast cancers and very ...
Mar 20, 2019
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A cellular identity switch protects a cancer-promoting genetic pathway from targeted therapy, researchers at The University of Texas MD Anderson Cancer Center today reported in Science Translational Medicine.
Mar 13, 2019
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Metastatic breast cancers treated with hormone therapy can become treatment-resistant when they acquire mutations in the human epidermal growth factor receptor 2 (HER2) that were not present in the original tumor, reports ...
Dec 11, 2018
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Elevated levels of chronic stress hormones, such as those produced by psychological distress, may promote resistance to drugs commonly used to treat lung cancer patients with EGFR mutations, according to new research from ...
Nov 8, 2017
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285
In one of the largest efforts to build a comprehensive catalog of genetic vulnerabilities in cancer, researchers from the Broad Institute of MIT and Harvard and Dana-Farber Cancer Institute have identified more than 760 genes ...
Jul 27, 2017
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105
Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, the Veterans Affairs Medical Center in Miami, and Shantou University Medical College in China, have shown that the ...
Dec 20, 2016
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