Cancer

Cancer: A mutation that breaks gene interplay in 3-D

Inside cells DNA is tightly wrapped around proteins and packed in a complex, 3-D structure called chromatin. Chromatin not only protects genetic material from damage, but also organizes the entire genome by regulating the ...

Medical research

Making 'sense' of the 'cart before the horse' in mammalian cells

A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome. ...

Cancer

Scientists find link between inflammation and cancer

Severe inflammation in tissues is often associated with the occurrence of cancer. The mechanism linking both these conditions is not clearly understood. Furthermore, inflamed and cancerous tissues contain a heterogenous mix ...

Neuroscience

Nature versus nurture and addiction

The progressive understanding of addiction as a disease rather than a choice has opened the door to better treatment and research, but there are aspects of addiction that make it uniquely difficult to treat.

Cancer

New drug targets for BRCA-driven cancer uncovered

BRCA1 and BRCA2 ("BReast CAncer genes") are critical tumor suppressor genes—women carrying a mutation in one of these genes have up to an 80 percent risk of developing breast cancer and a 50 percent risk of developing ovarian ...

Genetics

Gene therapy blocks peripheral nerve damage in mice

Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch. When axons are damaged, whether by injury or as a side effect of certain drugs, a program is triggered ...

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