For decades, scientists have been sequencing the DNA of many cancer types, identifying errors in the genetic code to help understand the formation of tumors, how they grow and what leads to their spread. But sometimes cancer ...
Nov 2, 2023
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Mutations in the PIK3CA gene that lead to elevated production of the PI3Ka protein are among the most frequent alterations found in cancer, including in approximately 40% of hormone receptor–positive breast cancers.
Nov 2, 2023
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The Wistar Institute's David B. Weiner and collaborators have engineered novel monoclonal antibodies that engage natural killer (NK) cells through a unique surface receptor that activates the immune system to fight against ...
Nov 1, 2023
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As people age, the DNA in their cells begins to accumulate genetic mutations. Mosaic chromosomal alterations (mCAs), a category of mutations acquired in blood cells, are linked with a 10-fold increased risk of developing ...
Nov 1, 2023
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Imagine the body's cells are well-behaved students in the classroom. The "teachers" are tumor suppressor genes, and they make sure cells follow the rules. But when tumor suppressor genes are away, cells may go astray.
Nov 1, 2023
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Breast cancer may be thought of as a disease that affects only women. It's the second-most common cancer diagnosed in women in the U.S., and it will affect one in eight women, according to the American Cancer Society. Much ...
Nov 1, 2023
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In an exciting scientific breakthrough, a team of researchers led by Professor Yehuda Tzfati from the Institute of Life Science at the Hebrew University and Professor Klaus Kaestner from the University of Pennsylvania Perelman ...
Oct 30, 2023
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Implementation of a digital risk assessment tool can identify patients with high-risk cancer susceptibility syndromes, according to a study presented at the annual meeting of the American College of Gastroenterology, held ...
Oct 27, 2023
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Viral infections are known to be a central cause of more than 10% of cancers worldwide. University of California researchers may have uncovered one of the key reasons why. Their findings were published today in PLOS Pathogens.
Oct 26, 2023
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A team of Penn State geneticists is pursuing the answers to an age-old question of human biology: the genetic origin of fundamental variations in skin pigmentation between people of different ethnicities. The link between ...
Oct 25, 2023
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