Oncology & Cancer

A potential new cancer target

The role of transforming growth factor beta (TGF-beta) in cancer progression is still not fully understood due its context-dependent biology.

Medical research

'Terminator' protein halts cancer-causing cellular processes

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

Oncology & Cancer

Notorious cancer protein mutations cooperate to proliferate disease

Understanding the genetic mutations and protein changes that take place in the progression of cancer is key to its treatment. Mutations in the gene TP53 and concomitant mutant p53 proteins in cancer cells have become notorious ...

Oncology & Cancer

Researchers study radiation resistance in brain cancer cells

In a vertical climb to avoid collision with a towering mountain, a plane ejects cargo to gain altitude. Investigators at the University of Minnesota showed that cancer cells perform similar feats in escaping the killing effects ...

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