Cancer cells are well-known as voracious energy consumers, but even veteran cancer-metabolism researcher Deepak Nagrath was surprised by their latest exploit: Experiments in his lab at Rice University show that some cancer ...
Mar 7, 2016
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Using a new approach, scientists at The Scripps Research Institute (TSRI) and collaborating institutions have discovered a novel drug candidate that could be used to treat certain types of breast cancer, lung cancer and melanoma.
Mar 7, 2016
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PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. ...
Mar 3, 2016
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Inhibiting the transfer of calcium ions into the cell's powerhouse is specifically toxic to cancer cells, according to an article published this week in Cell Reports by researchers from the Perelman School of Medicine at ...
Mar 3, 2016
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Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have pioneered a new method for conducting in-depth research on malignant tumors in patients, in the process discovering new complexities ...
Feb 4, 2016
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A new study of metabolic health risk factors in childhood cancer survivors showed increased risk for modifiable factors such as hypertension and overweight/obesity. These factors have been linked to the effects of chemotherapy ...
Jan 25, 2016
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UT Southwestern Medical Center researchers have found that cancer drugs known as CDK4/6-inhibitors alter the metabolism of pancreatic cancer cells, revealing a biologic vulnerability that could be exploited for therapeutic ...
Jan 21, 2016
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What can a rare genetic childhood disease teach us about cancer? Dr. Ayelet Erez of the Weizmann Institute's Biological Regulation Department says: "A single-mutation disease can act as a 'lens.' If we find exactly what malfunctions ...
Nov 30, 2015
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A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) identifies a key pathway used by cancer cells ...
Nov 9, 2015
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When cancer cells compete with immune cells for glucose, the cancer wins. As a result, the immune T cells are not healthy and don't have the weapons to kill the cancer.
Nov 2, 2015
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