In addition to their role in energy metabolism, mitochondria play important roles in other cellular processes, such as apoptosis, calcium signaling and the synthesis of certain biomolecules. Mitochondria have also been implicated ...
May 1, 2023
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Pancreatic cancers are deadly and hard to treat, in part because they are so often detected at an advanced stage; overall five-year survival rates are about 11%. Two separate labs at Boston Children's Hospital took out-of-the-box ...
Apr 25, 2023
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Metabolic (bariatric) surgery is more effective than medications and lifestyle interventions for the treatment of advanced non-alcoholic fatty liver disease.
Apr 20, 2023
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Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medications. This is the case, for example, with alpelisib, a drug that has been approved for ...
Apr 11, 2023
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A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now shown that with this ...
Apr 6, 2023
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Research from Johns Hopkins Kimmel Cancer Center experts revealed a type of RNA, previously considered to be "junk," that may help doctors distinguish and treat a subgroup of patients with medulloblastoma.
Mar 23, 2023
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Lung cancer patients can have their risk of dying accurately predicted within the last four weeks of life, a study involving University of Liverpool researchers has shown.
Feb 28, 2023
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Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune ...
Feb 14, 2023
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For up to 40 years, nearly 800,000 people from Sweden, Norway and Austria have been tracked based on how their BMI and metabolic health—that is, their blood pressure, blood glucose levels and blood fats—affect the risk ...
Feb 7, 2023
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For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme, called PI5P4Kα. The findings, published recently in Science Advances, could help address the growing threat ...
Feb 3, 2023
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