If metastases occur in the body, but the original tumor remains undetectable, this is referred to as "cancer of unknown primary" (CUP). But if information on the tissue of origin is missing, neither organ-specific chemotherapy ...
Aug 1, 2024
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People with a BRCA1 gene mutation, which increases breast and ovarian cancer risk, are also at increased risk of impaired fertility, Monash University-led research has confirmed in preclinical models and human tissue samples.
Jul 31, 2024
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An analysis of pre-treatment tumor specimens from 105 patients with localized muscle-invasive bladder cancer found that the presence of a mutation in any one of three genes, all known to be involved in DNA damage repair, ...
Jul 29, 2024
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More and more studies show that men face risks of cancer from BRCA1 and BRCA2 genetic mutations that are most often associated with breast and ovarian cancers in women.
Jul 26, 2024
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University of Toronto researchers have identified two genes that play a critical role in tumor growth in the pancreas—findings that have significant implications for understanding and treating pancreatic cancer.
Jul 25, 2024
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Cancer is caused by genetic changes that occur in our cells over time. There are two main types of changes, namely somatic mutations, which are alterations in the DNA sequence, and copy number alterations, which are changes ...
Jul 23, 2024
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Current screening protocols fail to catch a notable number of people carrying genetic mutations associated with hereditary breast and ovarian cancer syndrome and Lynch syndrome, which increase the risk of developing certain ...
Jul 17, 2024
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A study led by researchers at Brighton and Sussex Medical School (BSMS) has unveiled an approach to predicting the effectiveness of treatments for patients with diffuse large B-cell lymphoma (DLBCL), a common form of blood ...
Jul 15, 2024
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"Who will watch the watchers?" asked Roman poet Juvenal way back in the first century C.E. Nature has been addressing that very question for much, much longer. The human body contains proteins that are designed to protect ...
Jul 12, 2024
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Research led by the Cancer Biology Laboratory of the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, in collaboration with the Center for Genomic Regulation and the Murcian Institute of Biosanitary ...
Jul 8, 2024
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