More-effective therapies are greatly needed for children with the high-risk blood cancer T-cell acute lymphoblastic leukemia (T-ALL). St. Jude Children's Research Hospital scientists have leveraged the latest chemical technology ...
Aug 24, 2022
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It's a figure that stands out. Black women have a 36% higher breast cancer mortality rate than other races in spite of having a similar incidence to White women. Black women also are both more likely to be diagnosed with ...
Aug 24, 2022
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Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...
Aug 16, 2022
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A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, ...
Aug 15, 2022
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Genetic alterations in the FGFR2 gene occur in various cancer types and represent a promising target for therapies. However, clinical responses to available therapies remained variable and unpredictable, making it difficult ...
Aug 10, 2022
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In a study recently published in Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center (TTUHSC) School of Medicine Cancer Center, sought ...
Aug 10, 2022
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Sometimes too much of a good thing is not good at all. Inhibiting the function of the PD-1 protein, which blocks immune function, has shown high therapeutic efficacy in cancer immunotherapy. However, when this function is ...
Aug 9, 2022
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A new research perspective published in Oncoscienceexplores SLFN11's surveillance role in protein homeostasis.
Aug 3, 2022
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Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027.
Jul 28, 2022
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New research from VCU Massey Cancer Center published Thursday in Cell Reports has demonstrated that a novel targeted therapy could be an effective treatment option for a deadly pediatric cancer known as neuroblastoma.
Jul 28, 2022
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