While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies.
Sep 21, 2016
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An animal study suggests that resistance to tamoxifen therapy in some estrogen receptor positive breast cancers may originate from in utero exposure to endocrine disrupting chemicals. The study provides a new path forward ...
Sep 8, 2016
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Researchers at Bellvitge Biomedical Research Institute (IDIBELL) have published a study in Oncotarget that highlights the importance of the tumor environment as a source of resistance to treatment in colorectal cancer, the ...
Sep 6, 2016
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A team of scientists led by Dr Bhaskar Bhattacharya and Associate Professor Richie Soong from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) conducted a study on acquired ...
Sep 5, 2016
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With the right treatment schedule, medications known as hypoxia-activated prodrugs (HAPs) could help prevent drug resistance in a subtype of lung cancer, according to a study published in PLOS Computational Biology.
Aug 25, 2016
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Mutations in the BRCA1 gene are one of the most common risk factors for breast and ovarian cancers. Although tumors that harbor BRCA1 mutations initially respond well to cancer treatments, many tumors eventually become less ...
Jul 25, 2016
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A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. The findings, ...
Jul 20, 2016
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Epithelial ovarian cancer (EOC) is the most lethal disease among gynecologic malignancies. Patients with an advanced disease often relapse due to the development of chemoresistance. Chemotherapy failure is a consequence of ...
Jun 16, 2016
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By increasing the level of a specific microRNA (miRNA) molecule, researchers have for the first time restored chemotherapy sensitivity in vitro to a line of human pancreatic cancer cells that had developed resistance to a ...
May 27, 2016
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The rate at which genetically mutated cancer cells grow may help explain why patients with a common form of leukemia develop treatment resistance, according to new research led by a Weill Cornell Medicine investigator. The ...
May 25, 2016
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