A new study from the lab of University of Kentucky Markey Cancer Director Mark Evers, M.D., demonstrates the critical role of the hormone neurotensin in cell proliferation and stem cell function in the small intestine.
Oct 7, 2021
0
5
Circulating tumor cells (CTCs) with stem cell features use the adhesive protein ICAM1 to facilitate formation of CTC clusters, which can travel from primary tumors to other organs in the body, according to a Northwestern ...
Sep 23, 2021
0
21
McGill University researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation ...
Aug 31, 2021
1
76
More than 43,000 American women will die from breast cancer this year. Most of those deaths will occur after the cancer has spread to other organs, a process called metastasis. This involves at least five major steps. Two ...
Aug 18, 2021
0
296
As people age, mutations can build up in blood stem cells and their clones in a process known as age-related clonal hematopoiesis, or ARCH. ARCH can be a risk factor for acute myeloid leukemia (AML), a form of blood cancer. ...
Aug 17, 2021
0
316
In some children with acute myeloid leukemia, cancer cells have as many DNA changes as healthy blood stem cells. Researchers were surprised to find these children have a poorer chance of survival compared with children whose ...
Aug 6, 2021
0
49
Princess Margaret Cancer Centre researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number ...
Aug 2, 2021
0
325
Research published in Science Signaling identifies new ways that telomeres regulate the aggressiveness and survival of tumors, making them potentially vulnerable therapeutic targets for killing cancer. The discovery was made ...
Jul 30, 2021
0
467
A novel therapy engineered by Northwestern Medicine investigators improved progression-free and overall survival for patients with newly diagnosed malignant gliomas, according to results from a recent phase I clinical trial ...
Jul 30, 2021
0
79
Removing a protein that is often overexpressed in a rare and aggressive subtype of leukemia can help to slow the cancer's development and significantly increase the likelihood of survival, according to a study in mice led ...
Jul 29, 2021
0
231
