Medical investigators are theorizing that a combination of two treatments that activate myeloid cells may effectively treat a recalcitrant form of pancreatic cancer that thwarts conventional immunotherapy.
Prostate cancer is the most common cancer in men other than skin cancer, and more than 288,000 new cases are diagnosed every year, according to the American Cancer Society. The disease's fatality rate has decreased by more ...
Dec 21, 2023
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A team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification ...
Dec 21, 2023
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Despite their promise, immunotherapies fail to treat many cancers, including over 80% of some of the most advanced breast cancers. And many of those patients who do respond still experience metastases eventually. New research ...
Dec 20, 2023
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The p53 tumor suppressor protein is encoded by TP53, the most frequently mutated gene in cancer. A review article published in Nature Reviews Clinical Oncology by Professor Klas G Wiman and colleagues at the Department of ...
Dec 19, 2023
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Scientists have found an experimental small molecule that induces a form of cell death to kill a variety of cancers while enhancing the power of the immune system and leaving healthy cells totally unscathed.
The majority of patients with metastatic colorectal cancer whose cancer did not progress during initial treatment with immune checkpoint inhibitors (ICIs) had no disease progression two years after discontinuing treatment, ...
Dec 18, 2023
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How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo Clinic researchers studying pancreatic cancer—the third deadliest form of cancer in the U.S.—recently made a discovery that ...
Dec 18, 2023
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A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells. These effects dampen the capacity ...
Dec 15, 2023
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HBV-related HCC poses a significant global health challenge, characterized by its cellular diversity and complex tumor immune microenvironment. The increasing unmet need in HBV-HCC treatment highlights the need for a deeper ...
Dec 14, 2023
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