Oncology & Cancer

Potential therapeutic target for small cell lung cancer discovered

Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell lung cancer (SCLC) cells may decrease cancer cell differentiation and tumor ...

Oncology & Cancer

Q&A: When will patients see personalized cancer vaccines?

Catherine Wu has been a pioneer in a promising approach to fight cancer: vaccines that target specific immune-stimulating molecules, known as immunogenic peptides, generated by the distinct genetic mutations of any individual ...

Oncology & Cancer

New study seeks hereditary causes of childhood cancer

Follow-up and treatment of children with cancer is significantly improved when inherited genetic causes are also investigated, according to a new Swedish study. The results of the research involving some 50 researchers and ...

Oncology & Cancer

Novel mechanism supports antitumor response and T-cell survival

A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of ...

Oncology & Cancer

Improving cancer immunotherapy by prolonging T-cell survival

In the past decade, immunotherapy has emerged as the fourth pillar of cancer treatment, joining surgery, radiotherapy and chemotherapy. It is an approved treatment for 15 cancers, including melanoma and some types of lymphomas ...

Oncology & Cancer

Tumor deposits in colorectal and gastric cancers

Tumor deposits (TDs), initially recognized in colorectal cancer, have been identified in various other cancer types, including gastric cancer. It is defined as aggregates of tumor cells found in adipose and fibrous tissues ...

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