Unlocking the mystery of preexisting drug resistance: Study sheds light on cancer evolution
The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge.
15 hours ago
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The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge.
15 hours ago
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19
There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully—completely eliminating or greatly reducing cancer in particular patients—other times they don't work at all. It's ...
12 hours ago
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Colorectal cancer is the second leading cause of cancer deaths worldwide and the third most diagnosed cancer, affecting over a million people annually. The problem worsens if the tumor is metastatic, meaning it moves from ...
13 hours ago
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Immunotherapy can be a highly effective treatment for non-small cell lung cancer (NSCLC), but some patients are resistant to the therapy or develop intolerable side effects.
Jul 12, 2024
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A number of cancers, including certain brain and liver tumors, as well as myeloid leukemias, are driven by mutations in the enzyme isocitrate dehydrogenase 1, or IDH1. Drugs that block mutated IDH1 (mIDH1) have recently come ...
Jul 12, 2024
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As we age, our immune systems start to flag, leaving us more susceptible to cancer and infections—and less responsive to vaccines and cancer immunotherapies.
Jul 12, 2024
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The primary goal in cancer drug research is not merely to discover compounds that can destroy cancer cells, but to develop methods that specifically target and deliver these agents to cancer cells, sparing healthy ones.
Jul 12, 2024
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Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health ...
Jul 11, 2024
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Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.
Jul 11, 2024
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The artificial intelligence (AI) model GPT-4, known from its application in ChatGPT, shows impressive capabilities in biomedical research and can be used in many ways for simulations. A simulator developed at MedUni Vienna ...
Jul 11, 2024
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