A number of cancers, including certain brain and liver tumors, as well as myeloid leukemias, are driven by mutations in the enzyme isocitrate dehydrogenase 1, or IDH1. Drugs that block mutated IDH1 (mIDH1) have recently come ...
Jul 12, 2024
0
34
Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.
Jul 11, 2024
0
19
Acute lymphoblastic leukemia (ALL) is the most common cancer in children. This form of blood cancer, which also occurs in adults, is caused by malignantly degenerated precursor cells of certain white blood cells (B-cell precursors ...
Jul 1, 2024
0
0
As we age, our immune systems start to flag, leaving us more susceptible to cancer and infections—and less responsive to vaccines and cancer immunotherapies.
Jul 12, 2024
0
17
A new research paper was published on the cover of Aging, titled, "Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration."
Jun 17, 2024
0
0
Skin cancer is the most common form of cancer. When treated early, it's also the most curable type of cancer. Mohs surgery is one of the most successful surgical treatments for removing skin cancer.
Jun 18, 2024
0
2
Adding CD28 costimulation to cord blood-derived chimeric antigen receptor (CAR) natural killer (NK) cells targeting CD70+ cancers significantly enhanced antitumor efficacy and long-term cytotoxicity of the CAR NK cells, according ...
Jun 20, 2024
0
1
The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge.
Jul 15, 2024
0
19
Penis cancer is thankfully rare, but cases are rising. Some experts predict a 77% increase in penis cancer by 2050.
Jul 3, 2024
0
1
There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully—completely eliminating or greatly reducing cancer in particular patients—other times they don't work at all. It's ...
23 hours ago
0
14
