Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. The disease affects more than 12 million people worldwide, ...
Jan 22, 2024
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A protein found abundantly in breast cancers that are refractory to conventional treatments is thought to cause the development of metastasis. Targeting it would prevent metastatic spread and therefore increase patients' ...
Jan 31, 2024
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When Nancy Klauber-DeMore, M.D., began studying secreted frizzled-related protein 2, or SFRP2, it was as a breast cancer researcher and surgeon. Since she first showed in 2008 that the protein is involved in tumor growth ...
Dec 5, 2023
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A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells. These effects dampen the capacity ...
Dec 15, 2023
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Pleural mesothelioma (PM) is mainly caused by asbestos exposure and characterized by poor prognosis and limited therapeutic options. A recent research study led by Karin Schelch and Michael Grusch from MedUni Vienna identified ...
Oct 11, 2023
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Pfizer said Thursday it completed a $43 billion takeover of cancer-focused biotech company Seagen that the pharma giant said would enable it to double its oncology platform.
Dec 14, 2023
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Cancer patients who receive radiation during their treatment—and about half do—may face a lesser-known challenge: bone loss. The vital treatment for cancers of the head and neck, breast, cervix, prostate, and even eyes ...
Dec 6, 2023
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Women diagnosed with ovarian cancer may initially respond well to chemotherapy, but the majority of them will develop resistance to treatment and die from the disease. Now Northwestern Medicine scientists have discovered ...
Feb 21, 2024
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Knowing exactly what's inside a tumor can maximize our ability to fight cancer. But that knowledge doesn't come easy. Tumors are clusters of constantly changing cancer cells. Some become common cancer variants. Others morph ...
Feb 28, 2024
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The cells that make up our bodies are constantly communicating with each other, sometimes directly by physical touch. These interactions allow cells to respond to their neighbors, adapt to their surrounding environment and ...
Nov 16, 2023
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