Oncology & Cancer

Targeting turncoat immune cells to treat cancer

A Ludwig Cancer Research study has identified a mechanism by which regulatory T cells, which suppress immune responses, adapt their metabolism to thrive in the harsh microenvironment of the tumor. This mechanism, the study ...

Immunology

Predicting immunotherapy success

One of the frustrations with anti-cancer therapy is that no one drug fits all: Most work well in some people but have little effect in other patients with the same type of cancer. This is as true of the newer immunotherapy ...

Oncology & Cancer

Cancer immunotherapy target helps fight solid tumors

Yvonne Chen engineers immune cells to target their most evasive enemy: cancer. New cancer immunotherapies generate immune cells that are effective killers of blood cancers, but they have a hard time with solid tumors. Chen, ...

Oncology & Cancer

Study sheds light on regulation of breast cancer initiation

Tumor cells are characterized by high degree of heterogeneity and among them, tumor-initiating cells (TICs), sometimes also called cancer stem-like cells, are considered as the culprits of cancer development and progression, ...

Medical research

Cutting off kidney cancer at its roots

Scientists at the MDC have discovered stem cells responsible for the most common form of kidney cancer. The team of Walter Birchmeier has found a way to block the growth of these tumors in three models of the disease.

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