While lower vertebrates can repair their adult hearts after a heart attack, mammals—including humans—cannot. The ability to regenerate dead muscle tissue in mammalian hearts disappears just a few days after birth because ...
Jun 24, 2022
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Males and females differ in prevalence, treatment responses, and survival rates for a variety of diseases. For cardiac disease, women almost uniformly fare far worse than men. There are likely many reasons for this, and scientists ...
Oct 19, 2021
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Fatty acids are formed when fat breaks down during digestion. While many of the body's organs use glucose as their primary energy source, the heart derives most of its required energy (over 70%) from the oxidation of fatty ...
Jun 29, 2021
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The protein titin is a large structural component of the sarcomere—the machinery that mediates contraction of cardiac muscle cells. Despite its importance to the beating heart, little is known about titin turnover.
Dec 18, 2019
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Researchers from the National Institute for Physiological Sciences revealed the molecular mechanism underlying increased risk of heart failure during hemodynamic load by methylmercury exposure. They found that exposure of ...
Jun 26, 2019
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Injured hearts do not heal themselves. Heart muscle cells, or cardiomyocytes, do not proliferate as much as necessary to replace dead tissue with new, pumping cells. Consequently, most people who had a severe heart attack ...
Feb 14, 2019
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A new study by Professors Martti Juhola and Katriina Aalto-Setälä of the University of Tampere in Finland demonstrates that with the use of artificial intelligence and machine learning, it is possible not only to accurately ...
Jun 20, 2018
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Biophysicists from MIPT have studied the structure of a nanofibrous scaffold, as well as its interaction with rat cardiac cells. The study, which is part of the research into heart tissue regeneration, revealed that cardiomyocytes, ...
Mar 2, 2018
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In adult mammal hearts, cardiomyoctyes do not proliferate following damage such as that caused by myocardial infarction. However, in some mammals, cardiomyocyte proliferation occurs. "Neonatal cardiomyocytes proliferate, ...
May 29, 2017
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When the heart is subjected to stress, such as high blood pressure, it responds by expanding, both at the level of the whole organ and some of its chambers, and also at the level of single cells. Although the swelling of ...
Oct 31, 2016
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