MIV-711, a novel selective cathepsin K inhibitor, was not more effective than placebo for reducing pain related to knee osteoarthritis. However, MIV-711 significantly reduced bone and cartilage progression. Findings from ...
Dec 30, 2019
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Wake Forest Institute for Regenerative Medicine (WFIRM) scientists are the first to report using bioprinting to print a tracheal tissue construct comprised of multiple different functional materials. They printed different ...
Dec 04, 2019
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Researchers have developed a way to perform optical coherence tomography (OCT) in hard-to-reach areas of the body such as joints. The advance could help bring this high-resolution biomedical imaging technique to new surgical ...
Nov 12, 2019
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As a young anatomist, I was fascinated by an ancient Greek sculpture at the National Museum in Rome known as Boxer of the Quirinal. The bronze figure has dark voids for eye sockets and very odd ears. The sculptor depicted ...
Nov 04, 2019
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Humans have the ability to regrow cartilage, a new study has found.
Oct 18, 2019
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Contrary to popular belief, cartilage in human joints can repair itself through a process similar to that used by creatures such as salamanders and zebrafish to regenerate limbs, researchers at Duke Health found.
Oct 09, 2019
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More than 10 percent of Americans over age 60 experience knee pain related to osteoarthritis, the most common disease of the knee joint. Osteoarthritis of the knee causes pain, activity limitation, physical disability, reduced ...
Oct 08, 2019
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Organs, muscles and bones are composed of multiple types of cells and tissues that are carefully organized to carry out a specific function. For example, kidneys are able to filter waste from the blood because of how their ...
Sep 30, 2019
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The development of new bone can be a multistep process: first, stem cells differentiate into cartilage cells. Next, the cartilage cells become bone cells. But that's not all: the cells must experience some mechanical stresses ...
Aug 28, 2019
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Knee joint injuries, such as ligament rupture, are common in athletes. As the intact joint ligaments offer a precondition for joint stability, ligament injuries are often surgically reconstructed. However, in many cases these ...
Aug 20, 2019
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Cartilage is a type of dense connective tissue existing within many joints. It is composed of specialized cells called chondrocytes that produce a large amount of extracellular matrix composed of collagen fibers, abundant ground substance rich in proteoglycan, and elastin fibers. Cartilage is classified in three types, elastic cartilage, hyaline cartilage and fibrocartilage, which differ in the relative amounts of these three main components.
Cartilage is found in many areas in the body, including the articular surface of the bones, the rib cage, the ear, the nose, the bronchial tubes and the intervertebral discs. Its mechanical properties are intermediate between bone and dense connective tissue like tendon.
Unlike other connective tissues, cartilage does not contain blood vessels. The chondrocytes are fed by diffusion, helped by the pumping action generated by compression of the articular cartilage or flexion of the elastic cartilage. Thus, compared to other connective tissues, cartilage grows and repairs more slowly.
This text uses material from Wikipedia, licensed under CC BY-SA
