As a rubber-like elastic tissue with widely varying properties, cartilage lubricates joints to keep them healthy and in motion, and forms many of our internal structures, such as the intervertebral discs in the spine, the ...
May 22, 2020
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Hutchinson-Gilford progeria syndrome (HGPS) is a fatal condition that is especially prevalent in the skin, cardiovascular and the musculoskeletal systems. There exists a wide gap between existing knowledge of the disease ...
May 12, 2020
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Millions of Americans live with the pain and physical limitations of arthritis and other inflammatory diseases. Steroids and other drugs can offer relief, but they can also come with a host of serious side effects.
Mar 04, 2020
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In the event of a bone fracture, fatty acids in the blood signal to stem cells that they have to develop into bone-forming cells. If there are no blood vessels nearby, the stem cells end up forming cartilage. The finding ...
Feb 26, 2020
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People with osteoarthritis, or "wear and tear" arthritis, have limited treatment options: pain relievers or joint replacement surgery. Now, Salk researchers have discovered that a powerful combination of two experimental ...
Jan 22, 2020
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MIV-711, a novel selective cathepsin K inhibitor, was not more effective than placebo for reducing pain related to knee osteoarthritis. However, MIV-711 significantly reduced bone and cartilage progression. Findings from ...
Dec 30, 2019
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Wake Forest Institute for Regenerative Medicine (WFIRM) scientists are the first to report using bioprinting to print a tracheal tissue construct comprised of multiple different functional materials. They printed different ...
Dec 04, 2019
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Researchers have developed a way to perform optical coherence tomography (OCT) in hard-to-reach areas of the body such as joints. The advance could help bring this high-resolution biomedical imaging technique to new surgical ...
Nov 12, 2019
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As a young anatomist, I was fascinated by an ancient Greek sculpture at the National Museum in Rome known as Boxer of the Quirinal. The bronze figure has dark voids for eye sockets and very odd ears. The sculptor depicted ...
Nov 04, 2019
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Humans have the ability to regrow cartilage, a new study has found.
Oct 18, 2019
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Cartilage is a type of dense connective tissue existing within many joints. It is composed of specialized cells called chondrocytes that produce a large amount of extracellular matrix composed of collagen fibers, abundant ground substance rich in proteoglycan, and elastin fibers. Cartilage is classified in three types, elastic cartilage, hyaline cartilage and fibrocartilage, which differ in the relative amounts of these three main components.
Cartilage is found in many areas in the body, including the articular surface of the bones, the rib cage, the ear, the nose, the bronchial tubes and the intervertebral discs. Its mechanical properties are intermediate between bone and dense connective tissue like tendon.
Unlike other connective tissues, cartilage does not contain blood vessels. The chondrocytes are fed by diffusion, helped by the pumping action generated by compression of the articular cartilage or flexion of the elastic cartilage. Thus, compared to other connective tissues, cartilage grows and repairs more slowly.
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