Patients undergoing hip arthroscopy with high-grade cartilage damage do not see as positive results compared with patients with lower grade cartilage damage, according to research reported today at the American Orthopedic ...
Jul 11, 2021
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Immune rejection is one of the biggest obstacles to cell therapy. To solve this problem, researchers have been investigating iPS cells that have been gene edited so that they can evade the immune system. While this concept ...
Jul 07, 2021
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Articular cartilage is a connective tissue lining the surfaces of joints. When the cartilage severely wears down, it leads to osteoarthritis (OA), a debilitating disease that affects millions of people globally.
Jun 22, 2021
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A team of University of Alberta researchers has discovered a way to use 3-D bioprinting technology to create custom-shaped cartilage for use in surgical procedures. The work aims to make it easier for surgeons to safely restore ...
May 04, 2021
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Mammalian embryonic development is an extremely complex and precise process. Specific molecular events act as cues that tell cells in the embryo where to move and what type to mature into. The expression levels of different ...
Apr 14, 2021
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A new biosealant therapy may help to stabilize injuries that cause cartilage to break down, paving the way for a future fix or—even better—begin working right away with new cells to enhance healing, according to a new ...
Apr 09, 2021
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Orthopaedic researchers are one step closer to preventing life-long arm and leg deformities from childhood fractures that do not heal properly.
Mar 25, 2021
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An unfortunate biological "feed-forward" loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers at Duke University and Washington University in Saint Louis.
Mar 22, 2021
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A disease of the joints, osteoarthritis affects more than 30 million adults and is the fifth-leading cause of disability in the United States. In a new study, scientists have discovered the cellular pathway that leads to ...
Feb 10, 2021
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Working to develop new treatments for osteoarthritis, researchers at Washington University School of Medicine in St. Louis have genetically engineered cartilage to deliver an anti-inflammatory drug in response to activity ...
Jan 27, 2021
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Cartilage is a type of dense connective tissue existing within many joints. It is composed of specialized cells called chondrocytes that produce a large amount of extracellular matrix composed of collagen fibers, abundant ground substance rich in proteoglycan, and elastin fibers. Cartilage is classified in three types, elastic cartilage, hyaline cartilage and fibrocartilage, which differ in the relative amounts of these three main components.
Cartilage is found in many areas in the body, including the articular surface of the bones, the rib cage, the ear, the nose, the bronchial tubes and the intervertebral discs. Its mechanical properties are intermediate between bone and dense connective tissue like tendon.
Unlike other connective tissues, cartilage does not contain blood vessels. The chondrocytes are fed by diffusion, helped by the pumping action generated by compression of the articular cartilage or flexion of the elastic cartilage. Thus, compared to other connective tissues, cartilage grows and repairs more slowly.
This text uses material from Wikipedia, licensed under CC BY-SA
