Human SH2D1A mutations resulting in X-linked lymphoproliferative syndrome type 1 (XLP1) are associated with a unique susceptibility to the Epstein-Barr virus (EBV), which may lead to fatal infectious mononucleosis (FIM). ...
Nov 12, 2018
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A rare malignancy known as squamous cell carcinoma of the anal canal (SCCA) is on the increase, and now researchers have reported results of the first-ever phase II clinical trial results for treatment with the immunotherapy ...
Apr 18, 2016
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It is well known that chronic drinking is associated with an increased incidence and severity of respiratory infections. Previous research had demonstrated that an increase in disease severity to influenza virus (IAV) infections ...
Aug 26, 2014
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New research led by scientists at Beth Israel Deaconess Medical Center (BIDMC) helps explain the role of an immunosuppressive pathway associated with inflammatory bowel disease (IBD), a condition that develops in genetically ...
Nov 10, 2015
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Even as overall cancer incidence and mortality decrease in the United States, the number of people diagnosed with liver cancer is on the rise. Current therapies for liver cancer are largely ineffective, resulting in poor ...
Mar 13, 2019
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People with a rare genetic trait who are infected with HIV progress more slowly to AIDS than others. But even within this group, there are wide variations in time to progression. A new study illustrates in detail how the ...
Sep 19, 2012
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New research critical to treatment for chronic toxoplasmosis, one of the most common parasitic diseases worldwide, was published in the Journal of Experimental Medicine. Researchers from the George Washington University (GW) ...
Aug 1, 2016
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A single protein may tip the balance between ridding the body of a dangerous virus and enduring life-long chronic infection, according to a report appearing in The Journal of Experimental Medicine.
Sep 15, 2014
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(HealthDay)—A new test can predict the course of inflammatory bowel disease (IBD) in patients, according to a study published online April 27 in Gut.
May 9, 2019
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Among patients with stage IV melanoma who were being treated with the immunotherapeutic pembrolizumab (Keytruda), the ratio of a particular subset of immune cells in the blood to tumor burden correlated with clinical response, ...
Sep 27, 2016
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