Medical research

Predicting treatment outcome for leishmaniasis

For patients with cutaneous leishmaniasis, a skin infection transmitted by a sand fly that can in some cases lead to painful and disfiguring ulcers, treatment can be grueling. The first-line therapy offered to many requires ...

Immunology

Could cytotoxic T-cells be a key to longevity?

Scientists from the RIKEN Center for Integrative Medical Science (IMS) and Keio University School of Medicine in Japan have used single-cell RNA analysis to find that supercentenarians—meaning people over the age of 110—have ...

Medical research

Immunologists identify T cell homing beacons for lungs

Scientists have identified a pair of molecules critical for T cells, part of the immune system, to travel to and populate the lungs. A potential application could be strengthening vaccines against respiratory pathogens such ...

Diseases, Conditions, Syndromes

Withering away: How viral infection leads to cachexia

Many patients with chronic illnesses such as AIDS, cancer and autoimmune diseases suffer from an additional disease called cachexia. The complex, still poorly understood syndrome, with uncontrollable weight loss and shrinkage ...

Immunology

Study identifies viral peptides critical to natural HIV control

Investigators at the Ragon Institute of MGH, MIT and Harvard have used a novel approach to identify specific amino acids in the protein structure of HIV that appear critical to the ability of the virus to function and replicate. ...

Immunology

New proof that narcolepsy is an autoimmune disease

Researchers from the University of Copenhagen have discovered autoreactive cells in persons suffering from narcolepsy. This is a new, important proof that the sleep disorder is an autoimmune disease. This knowledge may lead ...

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