When we form a new memory, the brain undergoes physical and functional changes known collectively as a "memory trace." A memory trace represents the specific patterns of activity and structural modifications of neurons that ...
Jul 25, 2024
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The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...
Jul 22, 2024
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Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair. Understanding how these cells are activated in different scenarios is important for developing new medical treatments. ...
Jun 26, 2024
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Using animals to study heart disease doesn't always translate well to human health outcomes, and human heart cells available for research don't work outside the human body.
Jun 25, 2024
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Immune activation in a pregnant woman can have negative effects on the development of fetal brain microglia—or macrophage immune cells in the brain—and even lead to neurodevelopmental disorders in newborns.
Jun 10, 2024
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Checkpoint immunotherapy utilizing PD-1 blockade has become the standard of care for metastatic melanoma. While this treatment is effective in 40% of patients, the other 60% develop resistance, leading to tumor regrowth. ...
Jun 10, 2024
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Researchers have, for the first time, visualized the full network of blood vessels across the cortex of awake mice, finding that blood vessels rhythmically expand and contract, leading to "waves" washing across the surface ...
May 29, 2024
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According to the US Centers for Disease Control and Prevention, at least 5.8 million Americans are currently living with Alzheimer's disease, which is the most common form of dementia. There is no cure for Alzheimer's, in ...
May 22, 2024
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When the heart is injured, as in a myocardial infarction, the damaged heart muscle cannot regenerate—instead, scar tissue forms. Cardiomyocytes, the heart muscle cells that generate contractile force, are lost for good. ...
May 16, 2024
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An active lifestyle can change how the body burns saturated and unsaturated fat according to new research from the University of Aberdeen.
May 16, 2024
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