A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of ...
Oct 12, 2016
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Over a year into the COVID-19 pandemic, it's important to remind people who is more at risk of serious coronavirus disease 2019 (COVID-19) symptoms, which can vary widely. Some people have no symptoms at all, while others ...
Apr 28, 2021
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Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia - a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.
Jan 12, 2016
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The latest issue of the journal Cell carries an article that is likely to help solve one of the long-standing mysteries of biomedicine. In a study that challenges currently held views, researchers at the Instituto Gulbenkian ...
Apr 28, 2011
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New research has revealed that red blood cells function as critical immune sensors by binding cell-free DNA, called nucleic acid, present in the body's circulation during sepsis and COVID-19, and that this DNA-binding capability ...
Oct 20, 2021
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(HealthDay)—Growing numbers of Americans aren't getting enough iron in their diets most likely due to changes in farming practices and a shift away from red meat, researchers report.
Aug 4, 2021
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A daily hydroxyurea pill may finally bring some relief for young children living with the painful and deadly blood disease sickle cell anemia (SCA) in resource-challenged sub-Saharan Africa, where the disease is prevalent ...
Dec 2, 2018
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Gene therapy holds a lot of promise in medicine. If we could safely alter our own DNA, we might eliminate diseases our ancestors passed down to us.
Nov 27, 2018
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Red blood cells are on a wild ride. As they race through the body to deliver oxygen, they must maintain a distinct dimpled shape—and bounce back into form even after squishing through narrow capillaries. Red blood cells ...
Apr 4, 2018
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Two teams of researchers working independently have found success in trialing gene therapies targeting sickle-cell anemia. Both teams have published papers in the New England Journal of Medicine describing their work and ...
