Oncology & Cancer

Researchers show Myc protein is cancer's 'volume control'

(Medical Xpress)—A protein called Myc, commonly found at high levels inside cancer cells, fuels the disease by allowing cells to override their in-built self-destruct mechanisms, according to two new studies by US scientists.

Oncology & Cancer

Probing the mystery of how cancer cells die

You've probably never heard of 'sphingolipids' before. But these curiously named organic compounds play a vital role in one of humanity's most well-known diseases: cancer.

Neuroscience

Scientists show how nerve wiring self-destructs

Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the long wires that ...

Medical research

Resist! TAK1 enables endothelial cells to avoid apoptosis

Cell death is an important aspect of tissue homeostasis, as well as inflammation and disease pathogenesis related to infection, injury, and tumor growth. Tumor necrosis factor-α (TNFα) coordinates cell death in a variety ...

Oncology & Cancer

'Lone wolf' protein offers new pathway to cancer treatments

Structural biologists at St. Jude Children's Research Hospital have discovered how a key protein functions to trigger cell's suicide machinery, called apoptosis. The scientists found that the protein, called BOK, is controlled ...

Medical research

Some pathogens use immune systems against us

Every moment of every day, our immune systems are battling to keep us healthy against an onslaught from invading organisms. But some of these invaders have evolved to use our very defences against us, writes Dr Stephen Graham, ...

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