New research findings show in detail how self-reactive T cells—white blood cells that mistakenly attack healthy instead of infected cells, thereby causing an autoimmune or an inflammatory response—are held in check by ...
Jan 24, 2023
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Proteins do not have a single shape, but are more like dynamic robots. But—how do they actually move? And what does this tell us about their function? Laura Orellana describes the movement of proteins using computer simulations—and ...
Jan 16, 2023
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In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling ...
Jan 3, 2023
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Northwestern Medicine scientists have identified disease-causing DNA variants in two genes linked to neurodevelopmental deficits including microcephaly in children, according to findings published in Nature Communications.
Dec 15, 2022
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Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes—potentially paving the way for better and less toxic cancer drugs.
Nov 23, 2022
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Medulloblastoma is the most common form of malignant brain tumor in children, which often can be cured with operation, radiation and chemotherapy. But a distinct type of medulloblastoma has an increased risk of becoming resistant ...
Oct 28, 2022
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A new drug that inhibits an enzyme playing a crucial role in cell division and growth has shown signs of anti-cancer activity with manageable side effects in liver cancer patients who have been treated unsuccessfully previously ...
Oct 27, 2022
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Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs. ...
Oct 27, 2022
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The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer's disease (AD), according to a new study ...
Oct 25, 2022
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As heart cells mature in mice, the number of communication pathways called nuclear pores dramatically decreases, according to new research from University of Pittsburgh and UPMC scientists. While this might protect the organ ...
Oct 24, 2022
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