Gastroenterology

Can we harness intestinal cells to treat endocrine disorders?

Enteroendocrine cells punch above their weight. Constituting just about 1 percent of intestinal cells, they produce, as a group, around 15 different hormones. These not only regulate intestinal function and digestion, but ...

Medical research

Gene expression could ring early kidney disease alarm

Biomedical engineers at Duke University have developed a method to study how key cells in the kidneys become injured and deformed. The new model has revealed a significant mechanism behind severe kidney disease and pointed ...

Medical research

Old neurons can block neurogenesis in mice

Destroying senescent cells in the aging stem cell niche enhances hippocampal neurogenesis and cognitive function in mice, researchers report January 20 in the journal Stem Cell Reports.

Immunology

CRISPR screen identifies new anti-inflammatory drug target

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered. They report Nov. 11 in the ...

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